To be eligible for the INDIGO Study, participants must meet certain criteria. If you think you might be eligible, your doctor can help you review all of the eligibility requirements, including the key requirements set out below.
Key Eligibility Requirements1
Be at least 12 years old
Have Grade 2 oligodendroglioma or astrocytoma (low-grade glioma)
Do not have a need for immediate chemotherapy or radiation
Have an IDH1 or IDH2 gene-mutated disease (IDH mutation occur in about 70-80% of Grade 2 gliomas2)
Have had at least 1 prior surgery for glioma (biopsy, sub-total resection, gross-total resection). The most recent surgery must have occurred at least 1 year and not more than 5 years prior to the study
Have had no prior anti-cancer therapy other than surgery for treatment of glioma, including chemotherapy or radiation
Be able to carry on normal activity and to work with no special care needed, even if it is with some effort and signs or symptoms of the disease3
Measure at specific levels that demonstrate adequate bone marrow function, hepatic (liver) function, and renal (kidney) function
Are not taking lamotrigine as an anti-seizure medication
Do not have a known active Hepatitis B (HBV) or Hepatitis C (HCV) infection, known positive human immunodeficiency virus (HIV) antibody results, or acquired immunodeficiency syndrome (AIDS)-related illness. Patients with a sustained viral response to HCV treatment or immunity to prior HBV infection will be allowed to participate. Patients with chronic HBV that is adequately suppressed by institutional practice will be also be permitted.
How to Participate
To learn where the current INDIGO Study sites are and how you can participate, please see the Study Site Locator.
The effectiveness and safety of vorasidenib have not been established. There is no guarantee that vorasidenib will receive health authority approval or become commercially available in any country for the use being investigated.
You are about to leave this website and enter a website operated by an independent third party.
By clicking on a link, you may enter a different part of this website, or a website outside of www.indigostudy.com. Websites administered by third parties are governed by their own Legal and Privacy Policies. Servier assumes no responsibility nor does it control, endorse or guarantee any aspect of your use of any third-party sites. Additionally, the presence of this link does not imply the third-party site’s endorsement of Servier or this website.
We automatically collect information about you using cookies, web beacons, and similar technologies. We use these tools to analyze how our products perform and improve our services.